This trial is split up in two different exercises, called “Case 1” and “Case 2”.
In general, for Case 1 between 10 and 25 images of FISH results are made available online, together with the corresponding clinical case description and including the result of GTG banding, the indication for FISH analysis and the information on the applied probes.
As an alternative, every three to five years participants will receive cell suspension (dropped on slides) of a clinical case which has to be handled and analysed according to the participant’s own standard operation procedures. Under normal conditions of transport (by ordinary mail) the shipped samples are supposed to be stable for 14 days.
In addition, in Case 2 participants have to solve a theoretical problem dealing with the appropriate application of the rules of ISCN nomenclature.